Drug resistant pancreatic cancer cells exhibit altered biophysical interactions with stromal fibroblasts in imaging studies of 3D co-culture models

Abstract Interactions between tumor and stromal cells are well known to play prominent roles in progression of pancreatic ductal adenocarcinoma (PDAC). As knowledge of stromal crosstalk in PDAC has evolved, it has become clear that cancer associated fibroblasts can play both tumor promoting and tumo...

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Autores principales:	Eric Struth, Maryam Labaf, Vida Karimnia, Yiran Liu, Gwendolyn Cramer, Joanna B. Dahl, Frank J. Slack, Kourosh Zarringhalam, Jonathan P. Celli
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2024-09-01
Colección:	Scientific Reports
Acceso en línea:	https://doi.org/10.1038/s41598-024-71372-9
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