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Osteoprotegerin (OPG) Upregulation Activates Breast Stromal Fibroblasts and Enhances Their Pro-Carcinogenic Effects through the STAT3/IL-6 Signaling

Breast carcinomas are composed of cancer cells surrounded by various types of non-cancer cells such as fibroblasts. While active cancer-associated fibroblasts (CAFs) support tumor initiation and progression, quiescent breast stromal fibroblasts (BSFs) inhibit these effects through various cytokines...

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Auteurs principaux: Huda K. Al-Nasrallah, Mysoon M. Al-Ansari, Abdelilah Aboussekhra
Format: Artigo
Langue:Inglês
Publié: MDPI AG 2022-10-01
Collection:Cells
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Accès en ligne:https://www.mdpi.com/2073-4409/11/21/3369
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