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Osteoprotegerin (OPG) Upregulation Activates Breast Stromal Fibroblasts and Enhances Their Pro-Carcinogenic Effects through the STAT3/IL-6 Signaling

Breast carcinomas are composed of cancer cells surrounded by various types of non-cancer cells such as fibroblasts. While active cancer-associated fibroblasts (CAFs) support tumor initiation and progression, quiescent breast stromal fibroblasts (BSFs) inhibit these effects through various cytokines...

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Principais autores: Huda K. Al-Nasrallah, Mysoon M. Al-Ansari, Abdelilah Aboussekhra
格式: Artigo
語言:Inglês
出版: MDPI AG 2022-10-01
叢編:Cells
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在線閱讀:https://www.mdpi.com/2073-4409/11/21/3369
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