FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2
Abstract FBXW7 is a member of the F-box protein family, which functions as the substrate recognition component of the SCF E3 ubiquitin ligase. FBXW7 is a main tumor suppressor due to its ability to control proteasome-mediated degradation of several oncoproteins such as c-Jun, c-Myc, Cyclin E1, mTOR,...
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| Principais autores: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2023-03-01
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| coleção: | Cell Death and Disease |
| Acesso em linha: | https://doi.org/10.1038/s41419-023-05724-0 |
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