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FBXW2 suppresses proliferation and invasion of lung cancer cells by targeting SKP2 and β-catenin

F-box protein is a substrate-receptor of SKP1-Cullin1-F-box protein (SCF) E3 ligase, but the function of many family members remains elusive. We found that F-box and WD-repeat domain-containing 2 (FBXW2) inhibits proliferation and invasion of lung cancer cells by targeting S phase kinase-associated...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Fei Yang, Yi Sun
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Taylor & Francis Group 2019-07-01
Rangatū:Molecular & Cellular Oncology
Ngā marau:
Urunga tuihono:http://dx.doi.org/10.1080/23723556.2019.1607458
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