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Delayed vacuolation in mammalian cells caused by hypotonicity and ion loss

Abstract Prolonged exposure of mammalian cells to hypotonic environments stimulates the development of sometimes large and numerous vacuoles of unknown origin. Here, we investigate the nature and formation of these vacuoles, which we term LateVacs. Vacuolation starts after osmotic cell swelling has...

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Principais autores: Emily Zook, Yingzhou Edward Pan, Anna Wipplinger, Hubert H. Kerschbaum, Robert J. Clements, Markus Ritter, Tobias Stauber, Michael A. Model
格式: Artigo
语言:Inglês
出版: Nature Portfolio 2024-11-01
丛编:Scientific Reports
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在线阅读:https://doi.org/10.1038/s41598-024-79815-z
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