Deletion of platelet-derived growth factor receptor β suppresses tumorigenesis in metabolic dysfunction-associated steatohepatitis (MASH) mice with diabetes

Abstract The platelet-derived growth factor (PDGF) family contributes to the progression of steatohepatitis; however, changes in and the characteristics of isoform-specific expression remain unclear. Since diabetes is a major driver of metabolic dysfunction-associated steatohepatitis (MASH), we char...

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Autors principals:	Tsutomu Wada, Yuki Takeda, Akira Okekawa, Go Komatsu, Yuichi Iwasa, Yasuhiro Onogi, Ichiro Takasaki, Takeru Hamashima, Masakiyo Sasahara, Hiroshi Tsuneki, Toshiyasu Sasaoka
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2024-10-01
Col·lecció:	Scientific Reports
Matèries:	Hepatic stellate cells (HSC) MicroRNA Metabolic dysfunction-associated steatohepatitis (MASH) Platelet-derived growth factor (PDGF)
Accés en línia:	https://doi.org/10.1038/s41598-024-75713-6
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