Endoderm Jagged induces liver and pancreas duct lineage in zebrafish

The hepatopancreatic duct cells connect liver hepatocytes and pancreatic acinar cells to the intestine, but the mechanism for their lineage specification is unclear. Here, the authors reveal that Notch ligands Jagged1b and Jagged2b induce duct cell lineage in the liver and pancreas of the zebrafish.

Dades bibliogràfiques

Autors principals:	Danhua Zhang, Keith P. Gates, Lindsey Barske, Guangliang Wang, Joseph J. Lancman, Xin-Xin I. Zeng, Megan Groff, Kasper Wang, Michael J. Parsons, J. Gage Crump, P. Duc Si Dong
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2017-10-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-017-00666-6
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