Optimal control to reach eco-evolutionary stability in metastatic castrate-resistant prostate cancer.

In the absence of curative therapies, treatment of metastatic castrate-resistant prostate cancer (mCRPC) using currently available drugs can be improved by integrating evolutionary principles that govern proliferation of resistant subpopulations into current treatment protocols. Here we develop what...

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Hlavní autoři:	Jessica Cunningham, Frank Thuijsman, Ralf Peeters, Yannick Viossat, Joel Brown, Robert Gatenby, Kateřina Staňková
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2020-01-01
Edice:	PLoS ONE
On-line přístup:	https://doi.org/10.1371/journal.pone.0243386
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