Cannabis use by people with HIV is associated with an anti-inflammatory immunometabolic phenotype in monocyte-derived macrophages

Abstract Chronic neuroinflammation is associated with comorbidities in people with HIV (PWH) on antiretroviral therapy (ART). While cannabis use is associated with reduced neuroinflammation and neurocognitive impairment (NCI) in PWH, the underlying mechanisms are unknown. To address this gap in know...

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Principais autores:	Mary K. Ford, Peter W. Halcrow, Anna E. Laird, Bryant L. Avalos, Ali Boustani, Matthew Spencer, Jack I. Melcher, Kyle C. Walter, Derek D. Hong, Gail Funk, Elizabeth G. Searson, Alexandra A. Le, Ronald J. Ellis, Scott Letendre, Maria Cecilia Garibaldi Marcondes, Johannes CM Schlachetzki, Jennifer Iudicello, Jerel Adam Fields
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2026-04-01
Series:	Journal of Neuroinflammation
Assuntos:	HIV Cannabis Monocyte-derived Macrophages Immunometabolism Neurocognitive Impairment
Acceso en liña:	https://doi.org/10.1186/s12974-026-03779-2
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