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HolomiRA: a reproducible pipeline for miRNA binding site prediction in microbial genomes

Abstract Background Small RNAs, such as microRNAs (miRNAs), are candidates for mediating communication between the host and its microbiota, regulating bacterial gene expression and influencing microbiome functions and dynamics. Here, we introduce HolomiRA (Holobiome miRNA Affinity Predictor), a comp...

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Autors principals: Jennifer Jessica Bruscadin, Tainã Figueiredo Cardoso, Liliane Costa Conteville, Juliana Virginio da Silva, Adriana Mércia Guaratini Ibelli, Gabriel Alexander Colmenarez Pena, Thanny Porto, Priscila Silva Neubern de Oliveira, Bruno Gabriel Nascimento Andrade, Adhemar Zerlotini, Luciana Correia de Almeida Regitano
Format: Artigo
Idioma:Inglês
Publicat: BMC 2025-10-01
Col·lecció:BMC Bioinformatics
Matèries:
Holobiome
Host–pathogen interaction
Gene regulation
Accés en línia:https://doi.org/10.1186/s12859-025-06241-x
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