Spacio-Linear Screening for Ligand-Docking Cavities in Protein Structures: SLAM Algorithm

Identifying structurally similar ligand-binding sites in unrelated proteins can facilitate drug repurposing, reveal off-target effects, and deepen our understanding of protein function. A number of tools were developed for structural screening, but many of them suffer from limited sensitivity and sc...

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Bibliografiska uppgifter

Huvudupphov:	Julia Panov, Alexander Elbert, Dean S. Rosenthal, Moshe Levi, Konstantin Chumakov, Raul Andino, Leonid Brodsky, Hanoch Kaphzan
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	MDPI AG 2026-02-01
Serie:	Life
Ämnen:	binding site similarity structural alignment 3D screening protein ligand docking
Länkar:	https://www.mdpi.com/2075-1729/16/2/285
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