Covalent Inhibition of the <i>Human</i> 20S Proteasome with Homobelactosin C Inquired by QM/MM Studies
20S proteasome is a main player in the protein degradation pathway in the cytosol, thus intervening in multiple pivotal cellular processes. Over the years the proteasome has emerged as a crucial target for the treatment of many diseases such as neurodegenerative diseases, cancer, autoimmune diseases...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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MDPI AG
2022-04-01
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| Saila: | Pharmaceuticals |
| Gaiak: | |
| Sarrera elektronikoa: | https://www.mdpi.com/1424-8247/15/5/531 |
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