A high-resolution view of the immune and stromal cell response to Haemophilus ducreyi infection in human volunteers

ABSTRACT Haemophilus ducreyi causes the genital ulcer disease chancroid and cutaneous ulcers in children. To study its pathogenesis, we developed a human challenge model in which we infect the skin on the upper arm of human volunteers with H. ducreyi to the pustular stage of disease. The model has b...

Полное описание

Библиографические подробности

Главные авторы:	Julie A. Brothwell, Yuhui Wei, Jia Wang, Tingbo Guo, Chi Zhang, Kate R. Fortney, Rory Duplantier, Li Chen, Teresa A. Batteiger, Mark H. Kaplan, Stanley M. Spinola, Sha Cao
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology 2025-03-01
Серии:	mBio
Предметы:	Haemophilus ducreyi human infection scRNA-seq spatial transcriptomics
Online-ссылка:	https://journals.asm.org/doi/10.1128/mbio.03885-24
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!