A high-resolution view of the immune and stromal cell response to Haemophilus ducreyi infection in human volunteers

ABSTRACT Haemophilus ducreyi causes the genital ulcer disease chancroid and cutaneous ulcers in children. To study its pathogenesis, we developed a human challenge model in which we infect the skin on the upper arm of human volunteers with H. ducreyi to the pustular stage of disease. The model has b...

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Hlavní autoři:	Julie A. Brothwell, Yuhui Wei, Jia Wang, Tingbo Guo, Chi Zhang, Kate R. Fortney, Rory Duplantier, Li Chen, Teresa A. Batteiger, Mark H. Kaplan, Stanley M. Spinola, Sha Cao
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2025-03-01
Edice:	mBio
Témata:	Haemophilus ducreyi human infection scRNA-seq spatial transcriptomics
On-line přístup:	https://journals.asm.org/doi/10.1128/mbio.03885-24
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