Polygenic risk-stratified screening for nasopharyngeal carcinoma in high-risk endemic areas of China: a cost-effectiveness study

BackgroundNasopharyngeal carcinoma (NPC) has an extremely high incidence rate in Southern China, resulting in a severe disease burden for the local population. Current EBV serologic screening is limited by false positives, and there is opportunity to integrate polygenic risk scores for personalized...

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Hlavní autoři:	Da-Wei Yang, Jacob A. Miller, Wen-Qiong Xue, Minzhong Tang, Lin Lei, Yuming Zheng, Hua Diao, Tong-Min Wang, Ying Liao, Yan-Xia Wu, Xiao-Hui Zheng, Ting Zhou, Xi-Zhao Li, Pei-Fen Zhang, Xue-Yin Chen, Xia Yu, Fugui Li, Mingfang Ji, Ying Sun, Yong-Qiao He, Wei-Hua Jia
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-05-01
Edice:	Frontiers in Public Health
Témata:	polygenic risk stratification nasopharyngeal carcinoma screening cost-effectiveness modeling study
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fpubh.2024.1375533/full
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