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Potential of gut microbiota metabolites in treating COPD: network pharmacology and Mendelian randomization approaches

ObjectiveThe gut microbiota and its metabolites exert a significant influence on COPD, yet the underlying mechanisms remain elusive. We aim to holistically evaluate the role and mechanisms of the gut microbiota and its metabolites in COPD through network pharmacology and Mendelian randomization appr...

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Principais autores: Zhenghua Cao, Shengkun Zhao, Tong Wu, Feng Sun, Shaodan Hu, Li Shi
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2024-11-01
סדרה:Frontiers in Microbiology
נושאים:
network pharmacology
MR
COPD
biological network
Phenylacetylglutamine
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1416651/full
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