TREM2 suppresses the proinflammatory response to facilitate PRRSV infection via PI3K/NF-κB signaling.

Triggering receptor expressed on myeloid cells 2 (TREM2) serves as an anti-inflammatory receptor, negatively regulating the innate immune response. TREM2 is mainly expressed on dendritic cells and macrophages, the target cells of porcine reproductive and respiratory syndrome virus (PRRSV). Thus, we...

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Detalhes bibliográficos

Principais autores:	Zhenbang Zhu, Xiaoxiao Zhang, Wenjuan Dong, Xiaoying Wang, Sheng He, Hui Zhang, Xun Wang, Ruiping Wei, Yaosheng Chen, Xiaohong Liu, Chunhe Guo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2020-05-01
coleção:	PLoS Pathogens
Acesso em linha:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1008543&type=printable
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