TREM2 suppresses the proinflammatory response to facilitate PRRSV infection via PI3K/NF-κB signaling.

Triggering receptor expressed on myeloid cells 2 (TREM2) serves as an anti-inflammatory receptor, negatively regulating the innate immune response. TREM2 is mainly expressed on dendritic cells and macrophages, the target cells of porcine reproductive and respiratory syndrome virus (PRRSV). Thus, we...

Descripció completa

Dades bibliogràfiques

Autors principals:	Zhenbang Zhu, Xiaoxiao Zhang, Wenjuan Dong, Xiaoying Wang, Sheng He, Hui Zhang, Xun Wang, Ruiping Wei, Yaosheng Chen, Xiaohong Liu, Chunhe Guo
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2020-05-01
Col·lecció:	PLoS Pathogens
Accés en línia:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1008543&type=printable
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!