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Structural Determinants Responsible for the Preferential Insertion of Ribonucleotides by Bacterial NHEJ PolDom

The catalytic active site of the Polymerization Domain (PolDom) of bacterial Ligase D is designed to promote realignments of the primer and template strands and extend mispaired 3&#8242; ends. These features, together with the preferred use of ribonucleotides (<i>NTPs</i>) over deoxynucleotides (dNT...

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Bibliográfalaš dieđut
Váldodahkkit: Alejandro Sánchez-Salvador, Miguel de Vega
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2020-01-01
Ráidu:Biomolecules
Fáttát:
Liŋkkat:https://www.mdpi.com/2218-273X/10/2/203
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