Oxytocin exerts harmful cardiac repolarization prolonging effects in drug-induced LQTS

Background: Oxytocin is used therapeutically in psychiatric patients. Many of these also receive anti-depressant or anti-psychotic drugs causing acquired long-QT-syndrome (LQTS) by blocking HERG/IKr. We previously identified an oxytocin-induced QT-prolongation in LQT2 rabbits, indicating potential h...

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التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Paul Kreifels, Ilona Bodi, Tibor Hornyik, Gerlind Franke, Stefanie Perez-Feliz, R. Lewetag, Robin Moss, Alessandro Castiglione, David Ziupa, Manfred Zehender, Michael Brunner, Christoph Bode, Katja E. Odening
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Elsevier 2022-06-01
سلاسل:	International Journal of Cardiology: Heart & Vasculature
الموضوعات:	Acquired long-QT syndrome Arrhythmia mechanisms Drug induced QT-prolongation Ion channels
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S2352906722000501
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!