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ESWT attenuates compressive stress-induced cartilaginous endplate degeneration via modulation of the SOST/Wnt/β-catenin signaling pathway

IntroductionCartilaginous endplate (CEP) degeneration is a critical contributor to intervertebral disc degeneration (IVDD) and is frequently induced by sustained compressive stress. Extracorporeal Shockwave Therapy (ESWT) has shown therapeutic potential in promoting disc repair; however, the underly...

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Principais autores: Pan Xiang, Junjun Hou, Chao Yang, Ting Liang, Wenbin Cai, Fanlei Yang, Jing Yang, Hao Xu, Zongping Luo, Yanjun Che
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2026-06-01
סדרה:Frontiers in Bioengineering and Biotechnology
נושאים:
cartilaginous endplate
extracorporeal shockwave therapy
intervertebral disc degeneration
mechanical stimulation
SOST
Wnt/β-catenin
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fbioe.2026.1769920/full
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