Human cartilaginous endplate degeneration is induced by calcium and the extracellular calcium-sensing receptor in the intervertebral disc

The cartilaginous endplates (CEPs) are thin layers of hyaline cartilage found adjacent to intervertebral discs (IVDs). In addition to providing structural support, CEPs regulate nutrient and metabolic exchange in the disc. In IVD pathogenesis, CEP undergoes degeneration and calcification, compromisi...

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Principais autores:	MP Grant, LM Epure, R Bokhari, P Roughley, J Antoniou, F Mwale
Format:	Artigo
Jezik:	Inglês
Izdano:	Forum Multimedia Publishing LLC 2016-07-01
Serija:	European Cells & Materials
Teme:	Intervertebral disc degeneration cartilaginous endplate calcification calcium extracellular calcium-sensing receptor disc nutrition
Online dostop:	http://www.ecmjournal.org/papers/vol032/pdf/v032a09.pdf
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