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PDZK1 inhibits MRP2-mediated oxaliplatin chemosensitivity in hepatocellular carcinoma

Abstract Recurrence after oxaliplatin chemotherapy is a major challenge in the treatment of advanced hepatocellular carcinoma patients. Differential expression gene analysis and Kaplan-Meier curves were screened biomarkers associated with OXA-treated recurrence in GSE51951, TCGA-LIHC, and Chinese Li...

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Principais autores: Zeqi Duan, Jinyu Li, Chao Ren, Yi Chen, Duiping Feng, Yanbo Ma, Chunjuan Zhao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2025-04-01
coleção:Scientific Reports
Assuntos:
Hepatocellular carcinoma
PDZK1
Oxaliplatin
MRP2
Chemosensitivity
Acesso em linha:https://doi.org/10.1038/s41598-025-98085-x
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