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Development of a robust induced pluripotent stem cell atrial cardiomyocyte differentiation protocol to model atrial arrhythmia

Abstract Background Atrial fibrillation is the most common arrhythmia syndrome and causes significant morbidity and mortality. Current therapeutics, however, have limited efficacy. Notably, many therapeutics shown to be efficacious in animal models have not proved effective in humans. Thus, there is...

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Principais autores: Jordan Thorpe, Matthew D. Perry, Osvaldo Contreras, Emily Hurley, George Parker, Richard P. Harvey, Adam P. Hill, Jamie I. Vandenberg
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2023-07-01
Series:Stem Cell Research & Therapy
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Acceso en liña:https://doi.org/10.1186/s13287-023-03405-5
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