Development of a robust induced pluripotent stem cell atrial cardiomyocyte differentiation protocol to model atrial arrhythmia

Abstract Background Atrial fibrillation is the most common arrhythmia syndrome and causes significant morbidity and mortality. Current therapeutics, however, have limited efficacy. Notably, many therapeutics shown to be efficacious in animal models have not proved effective in humans. Thus, there is...

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Κύριοι συγγραφείς:	Jordan Thorpe, Matthew D. Perry, Osvaldo Contreras, Emily Hurley, George Parker, Richard P. Harvey, Adam P. Hill, Jamie I. Vandenberg
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2023-07-01
Σειρά:	Stem Cell Research & Therapy
Θέματα:	Atrial cardiomyocyte Stem cells Cardiac Arrhythmias Atrial fibrillation
Διαθέσιμο Online:	https://doi.org/10.1186/s13287-023-03405-5
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