Fluvastatin suppresses hemin-induced cell death, reactive oxygen species generation, and elevated labile iron pool
Background: In transfusion-related iron overload, macrophage/reticuloendothelial cells are the first site of haem-derived iron accumulation. The prevention of haem-induced cytotoxicity in macrophages may represent a target for iron overload treatment. Deferasirox, an oral iron chelator, has been use...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2024-12-01
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| Col·lecció: | Hematology, Transfusion and Cell Therapy |
| Matèries: | |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S2531137924028323 |
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