From tobacco smoking to cancer mutational signature: a mediation analysis strategy to explore the role of epigenetic changes
Abstract Background Tobacco smoking is associated with a unique mutational signature in the human cancer genome. It is unclear whether tobacco smoking-altered DNA methylations and gene expressions affect smoking-related mutational signature. Methods We systematically analyzed the smoking-related DNA...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BMC
2020-09-01
|
| Seri Bilgileri: | BMC Cancer |
| Konular: | |
| Online Erişim: | http://link.springer.com/article/10.1186/s12885-020-07368-1 |
| Etiketler: |
Etiket eklenmemiş, İlk siz ekleyin!
|