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When two are better than one: Modeling the mechanisms of antibody mixtures.

It is difficult to predict how antibodies will behave when mixed together, even after each has been independently characterized. Here, we present a statistical mechanical model for the activity of antibody mixtures that accounts for whether pairs of antibodies bind to distinct or overlapping epitope...

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Autori principali: Tal Einav, Jesse D Bloom
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2020-05-01
Serie:PLoS Computational Biology
Accesso online:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1007830&type=printable
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