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Decoy receptor 2 mediates the apoptosis-resistant phenotype of senescent renal tubular cells and accelerates renal fibrosis in diabetic nephropathy

Abstract Apoptotic resistance leads to persistent accumulation of senescent cells and sustained expression of a senescence-associated secretory phenotype, playing an essential role in the progression of tissue fibrosis. However, whether senescent renal tubular epithelial cells (RTECs) exhibit an apo...

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Xehetasun bibliografikoak
Egile Nagusiak: Jia Chen, Ke-hong Chen, Li-ming Wang, Jia Luo, Quan-you Zheng, Ya-ni He
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2022-06-01
Saila:Cell Death and Disease
Sarrera elektronikoa:https://doi.org/10.1038/s41419-022-04972-w
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