High Oestrogen receptor alpha expression correlates with adverse prognosis and promotes metastasis in colorectal cancer

Abstract In normal colon tissue, oestrogen receptor alpha (ERα) is expressed at low levels, while oestrogen receptor beta (ERβ) is considered the dominant subtype. However, in colon carcinomas, the ERα/β ratio is often increased, an observation that prompted us to further investigate ERα’s role in c...

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Hlavní autoři:	Geriolda Topi, Shakti Ranjan Satapathy, Souvik Ghatak, Karin Hellman, Fredrik Ek, Roger Olsson, Roy Ehrnström, Marie-Louise Lydrup, Anita Sjölander
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-03-01
Edice:	Cell Communication and Signaling
Témata:	Oestrogen receptor alpha Colorectal cancer Cysteinyl leukotriene receptors Metastasis Zebrafish PPT
On-line přístup:	https://doi.org/10.1186/s12964-024-01582-1
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