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High Oestrogen receptor alpha expression correlates with adverse prognosis and promotes metastasis in colorectal cancer

Abstract In normal colon tissue, oestrogen receptor alpha (ERα) is expressed at low levels, while oestrogen receptor beta (ERβ) is considered the dominant subtype. However, in colon carcinomas, the ERα/β ratio is often increased, an observation that prompted us to further investigate ERα’s role in c...

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Bibliografiske detaljer
Principais autores: Geriolda Topi, Shakti Ranjan Satapathy, Souvik Ghatak, Karin Hellman, Fredrik Ek, Roger Olsson, Roy Ehrnström, Marie-Louise Lydrup, Anita Sjölander
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-03-01
Serier:Cell Communication and Signaling
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Online adgang:https://doi.org/10.1186/s12964-024-01582-1
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