LDL receptor deficiency or apoE mutations prevent remnant clearance and induce hypertriglyceridemia in mices⃞
We have used adenovirus-mediated gene transfer and bolus injection of purified apolipoprotein E (apoE) in mice to determine the contribution of LDL receptor family members in the clearance of apoE-containing lipoproteins in vivo and the factors that trigger hypertriglyceridemia. A low dose [5 × 108...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2006-03-01
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| Serie: | Journal of Lipid Research |
| Soggetti: | |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S0022227520336063 |
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