Synthesis and Antidiabetic Evaluation of Triazole-Linked Thiazolidine-2,4-dione Hybrids as α-Glucosidase and α-Amylase Inhibitors

A series of 1,2,3-triazole-linked-thiazolidine-2,4-dione hybrids (<b>SDP1–SDP15</b>) were designed, synthesized, and evaluated for their antidiabetic potential. All structures were characterized by FT-IR and NMR spectroscopy (¹H and ¹³C). All derivatives exhibited significant i...

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Hauptverfasser:	Subhayan Das Pal, Yukta Sao, Sujeet Kumar, Nishith Teraiya, Basavaraj Metikurki, Shankar G. Alegaon, Sanjana S. Prakash, Gururaj Kudur Jayaprakash, Subhas S. Karki
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2026-06-01
Schriftenreihe:	Chemistry
Schlagworte:	type 2 diabetes mellitus thiazolidinedione-triazole hybrids α-amylase α-glucosidase
Online-Zugang:	https://www.mdpi.com/2624-8549/8/6/77
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