High throughput sequencing reveals alterations in the recombination signatures with diminishing Spo11 activity.
Spo11 is the topoisomerase-like enzyme responsible for the induction of the meiosis-specific double strand breaks (DSBs), which initiates the recombination events responsible for proper chromosome segregation. Nineteen PCR-induced alleles of SPO11 were identified and characterized genetically and cy...
Salvato in:
| Autori principali: | , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science (PLoS)
2013-10-01
|
| Serie: | PLoS Genetics |
| Accesso online: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1003932&type=printable |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|