High throughput sequencing reveals alterations in the recombination signatures with diminishing Spo11 activity.
Spo11 is the topoisomerase-like enzyme responsible for the induction of the meiosis-specific double strand breaks (DSBs), which initiates the recombination events responsible for proper chromosome segregation. Nineteen PCR-induced alleles of SPO11 were identified and characterized genetically and cy...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science (PLoS)
2013-10-01
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| Seria: | PLoS Genetics |
| Dostęp online: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1003932&type=printable |
| Etykiety: |
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