Non-electron transfer chain mitochondrial defects differently regulate HIF-1α degradation and transcription
Mitochondria are the main consumers of molecular O2 in a cell as well as an abundant source of reactive oxygen species (ROS). Both, molecular oxygen and ROS are powerful regulators of the hypoxia-inducible factor-1α-subunit (HIF-α). While a number of mechanisms in the oxygen-dependent HIF-α regulati...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2017-08-01
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| coleção: | Redox Biology |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2213231717301490 |
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