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4322 Structure-guided design of the TIL1383I T cell receptor

OBJECTIVES/GOALS: Our goal is to employ a structure-guided design approach to engineering a safer and more effective variant of the TIL1383I T cell receptor (TCR) currently under study in clinical trials for malignant melanoma METHODS/STUDY POPULATION: Using our unpublished structure of TIL1383I we...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Jesus Alonso, Nishant Singh, Jason Devlin, Lauren Davancaze, Brian Baker
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Cambridge University Press 2020-06-01
Rangatū:Journal of Clinical and Translational Science
Urunga tuihono:https://www.cambridge.org/core/product/identifier/S205986612000093X/type/journal_article
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