QR Code

Genetic Implication of Specific Glutamatergic Neurons of the Prefrontal Cortex in the Pathophysiology of Schizophrenia

Background: The prefrontal cortex (PFC) has been strongly implicated in the pathophysiology of schizophrenia. Here, we combined high-resolution single-nuclei RNA sequencing data from the human PFC with large-scale genomic data for schizophrenia to identify constituent cell populations likely to medi...

Full description

Saved in:
Main Authors: Claire E. Tume, Sophie L. Chick, Peter A. Holmans, Elliott Rees, Michael C. O’Donovan, Darren Cameron, Nicholas J. Bray
Format: Artigo
Language:Inglês
Published: Elsevier 2024-09-01
Series:Biological Psychiatry Global Open Science
Subjects:
Gene expression
Genetic
Genome-wide association study (GWAS)
Prefrontal cortex
Rare variant
Schizophrenia
Online Access:http://www.sciencedirect.com/science/article/pii/S2667174324000582
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items