Genetic Implication of Specific Glutamatergic Neurons of the Prefrontal Cortex in the Pathophysiology of Schizophrenia

Background: The prefrontal cortex (PFC) has been strongly implicated in the pathophysiology of schizophrenia. Here, we combined high-resolution single-nuclei RNA sequencing data from the human PFC with large-scale genomic data for schizophrenia to identify constituent cell populations likely to medi...

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Egile Nagusiak:	Claire E. Tume, Sophie L. Chick, Peter A. Holmans, Elliott Rees, Michael C. O’Donovan, Darren Cameron, Nicholas J. Bray
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Elsevier 2024-09-01
Saila:	Biological Psychiatry Global Open Science
Gaiak:	Gene expression Genetic Genome-wide association study (GWAS) Prefrontal cortex Rare variant Schizophrenia
Sarrera elektronikoa:	http://www.sciencedirect.com/science/article/pii/S2667174324000582
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