Distinct functions of cardiac β-adrenergic receptors in the T-tubule vs. outer surface membrane

β-Adrenoceptors (β-ARs) regulate cardiac function during sympathetic nerve stimulation. β-ARs are present in both the cardiac T-tubule (TTM) and outer surface membrane (OSM), but how their location impacts their function is unknown. Here, we developed a technology based on size exclusion to explore...

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التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	George WP Madders, Marion Barthé, Flora Lefebvre, Emilie Langlois, Florence Lefebvre, Patrick Lechêne, Maya Dia, Xavier Iturrioz, Catherine Llorens-Cortes, Tâp Ha-Duong, Laurence Moine, Nicolas Tsapis, Rodolphe Fischmeister
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	eLife Sciences Publications Ltd 2025-09-01
سلاسل:	eLife
الموضوعات:	T-tubules membrane compartmentation β-adrenergic receptors PEGylation cardiomyocyte cyclic AMP
الوصول للمادة أونلاين:	https://elifesciences.org/articles/84243
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!