Image-Driven Modeling of Nanoscopic Cardiac Function: Where Have We Come From, and Where Are We Going?

Complementary developments in microscopy and mathematical modeling have been critical to our understanding of cardiac excitation–contraction coupling. Historically, limitations imposed by the spatial or temporal resolution of imaging methods have been addressed through careful mathematical interroga...

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Główni autorzy:	William E. Louch, Harmonie Perdreau-Dahl, Andrew G. Edwards
Format:	Artigo
Język:	Inglês
Wydane:	Frontiers Media S.A. 2022-03-01
Seria:	Frontiers in Physiology
Hasła przedmiotowe:	excitation contraction coupling (ECC) ryanodine receptor (RyR) super resolution microscopy calcium induced calcium release mathematical modeling
Dostęp online:	https://www.frontiersin.org/articles/10.3389/fphys.2022.834211/full
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