TLR4 Targeting as a Promising Therapeutic Strategy for Alzheimer Disease Treatment
Alzheimer disease (AD) is a devastating neurodegenerative disorder characterized by extracellular accumulation of amyloid-beta and formation of intracellular neurofibrillary tangles. Microglia activation and neuroinflammation play important roles in the pathogenesis of AD; Toll-like receptor 4 (TLR4...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2020-12-01
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| Serie: | Frontiers in Neuroscience |
| Soggetti: | |
| Accesso online: | https://www.frontiersin.org/articles/10.3389/fnins.2020.602508/full |
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