TLR4 Targeting as a Promising Therapeutic Strategy for Alzheimer Disease Treatment
Alzheimer disease (AD) is a devastating neurodegenerative disorder characterized by extracellular accumulation of amyloid-beta and formation of intracellular neurofibrillary tangles. Microglia activation and neuroinflammation play important roles in the pathogenesis of AD; Toll-like receptor 4 (TLR4...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020-12-01
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| coleção: | Frontiers in Neuroscience |
| Assuntos: | |
| Acesso em linha: | https://www.frontiersin.org/articles/10.3389/fnins.2020.602508/full |
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