Exploiting the Potential of <i>Drosophila</i> Models in Lysosomal Storage Disorders: Pathological Mechanisms and Drug Discovery

Lysosomal storage disorders (LSDs) represent a complex and heterogeneous group of rare genetic diseases due to mutations in genes coding for lysosomal enzymes, membrane proteins or transporters. This leads to the accumulation of undegraded materials within lysosomes and a broad range of severe clini...

Descrición completa

Detalles Bibliográficos

Principais autores:	Laura Rigon, Concetta De Filippis, Barbara Napoli, Rosella Tomanin, Genny Orso
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2021-03-01
Series:	Biomedicines
Assuntos:	lysosomal storage disorders <i>Drosophila melanogaster</i> animal model mucopolysaccharidosis sphingolipidosis mucolipidosis
Acceso en liña:	https://www.mdpi.com/2227-9059/9/3/268
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!