Exploiting the Potential of <i>Drosophila</i> Models in Lysosomal Storage Disorders: Pathological Mechanisms and Drug Discovery

Lysosomal storage disorders (LSDs) represent a complex and heterogeneous group of rare genetic diseases due to mutations in genes coding for lysosomal enzymes, membrane proteins or transporters. This leads to the accumulation of undegraded materials within lysosomes and a broad range of severe clini...

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Библиографические подробности

Главные авторы:	Laura Rigon, Concetta De Filippis, Barbara Napoli, Rosella Tomanin, Genny Orso
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2021-03-01
Серии:	Biomedicines
Предметы:	lysosomal storage disorders <i>Drosophila melanogaster</i> animal model mucopolysaccharidosis sphingolipidosis mucolipidosis
Online-ссылка:	https://www.mdpi.com/2227-9059/9/3/268
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