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Down-regulated GAS6 impairs synovial macrophage efferocytosis and promotes obesity-associated osteoarthritis

Obesity has always been considered a significant risk factor in osteoarthritis (OA) progression, but the underlying mechanism of obesity-related inflammation in OA synovitis remains unclear. The present study found that synovial macrophages infiltrated and polarized in the obesity microenvironment a...

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Bibliografiske detaljer
Principais autores: Zihao Yao, Weizhong Qi, Hongbo Zhang, Zhicheng Zhang, Liangliang Liu, Yan Shao, Hua Zeng, Jianbin Yin, Haoyan Pan, Xiongtian Guo, Anling Liu, Daozhang Cai, Xiaochun Bai, Haiyan Zhang
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2023-05-01
Serier:eLife
Fag:
Online adgang:https://elifesciences.org/articles/83069
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