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MRGPRX2-mediated mast cell activation by substance P from overloaded human tenocytes induces inflammatory and degenerative responses in tendons

Abstract Mast cells are immune cells minimally present in normal tendon tissue. The increased abundance of mast cells in tendinopathy biopsies and at the sites of tendon injury suggests an unexplored role of this cell population in overuse tendon injuries. Mast cells are particularly present in tend...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Rouhollah Mousavizadeh, Charlie M. Waugh, Robert G. McCormack, Brian E. Cairns, Alex Scott
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Nature Portfolio 2024-06-01
Цуврал:Scientific Reports
Онлайн хандалт:https://doi.org/10.1038/s41598-024-64222-1
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