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MRGPRX2-mediated mast cell activation by substance P from overloaded human tenocytes induces inflammatory and degenerative responses in tendons

Abstract Mast cells are immune cells minimally present in normal tendon tissue. The increased abundance of mast cells in tendinopathy biopsies and at the sites of tendon injury suggests an unexplored role of this cell population in overuse tendon injuries. Mast cells are particularly present in tend...

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Váldodahkkit: Rouhollah Mousavizadeh, Charlie M. Waugh, Robert G. McCormack, Brian E. Cairns, Alex Scott
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Nature Portfolio 2024-06-01
Ráidu:Scientific Reports
Liŋkkat:https://doi.org/10.1038/s41598-024-64222-1
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