Redox-dependent protein S-glutathionylation governs azacitidine sensitivity and resistance in AML

Disruption of redox metabolism is a hallmark of drug-resistant cancer cells, representing a major obstacle to the effective treatment of acute myeloid leukemia (AML). While recent studies have highlighted the importance of redox balance in AML therapy, the specific contribution of protein redox sign...

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Bibliografski detalji

Glavni autori:	Dušan Nemes, Michaela Myšáková, Lubomír Minařík, Anna Jonášová, Tomáš Stopka, Kristýna Gloc Pimková
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2026-02-01
Serija:	Redox Biology
Teme:	Drug resistance Hypomethylation therapy Azacitidine S-glutathionylation Cysteine oxidation Redox proteomics
Online pristup:	http://www.sciencedirect.com/science/article/pii/S2213231725004719
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